Princess Alexandra Hospital and Translational Research Institute cement Brisbane's health research ambitions

Princess Alexandra Hospital in Brisbane's southern suburbs has established a research partnership with the Translational Research Institute (TRI) that has made the PA Hospital precinct one of Australia's most active clinical research environments. The TRI, which brings together four universities and the Metro South Health service, provides the infrastructure for translating laboratory discoveries into clinical applications through a model of co-location that reduces the friction between bench and bedside research.

The research programs active at the PA-TRI precinct span cancer biology, infectious disease, cardiovascular medicine, metabolic disease and regenerative medicine. Each of these areas benefits from the clinical trial infrastructure that the PA Hospital provides and the laboratory capability that the TRI houses, creating a research environment that is attractive to international scientists and to the pharmaceutical and biotechnology companies that partner on clinical development programs.

Commercial partnerships between TRI researchers and industry have generated licensing income, spinout companies and collaborative research agreements that contribute to Queensland's biomedical industry ecosystem. The state government has recognised the TRI as a strategic asset for Queensland's knowledge economy and has maintained investment in its operations through funding arrangements that support the infrastructure costs of complex research enterprise.

Training of the next generation of clinician-researchers is a core function of the PA-TRI relationship, with programs that allow medical residents and registrars to integrate research activities into their clinical training. This model is important for sustaining the pipeline of clinician-researchers who can bridge the gap between clinical practice and laboratory science that translational research requires.

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